A Mollusk Retinoic Acid Receptor (RAR) Ortholog Sheds Light on the Evolution of Ligand Binding

Nuclear receptors are transcription factors that regulate networks of target genes in response to small molecules. There is a strong bias in our knowledge of these receptors because they were mainly characterized in classical model organisms, mostly vertebrates. Therefore, the evolutionary origins o...

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Bibliographic Details
Main Authors: Gutierrez-Mazariegos, Juliana, Nadendla, Eswar Kumar, Lima, Daniela, Pierzchalski, Keely, Jones, Jace W., Kane, Maureen, Nishikawa, Jun-Ichi, Hiromori, Youhei, Nakanishi, Tsuyoshi, Santos, Miguel M., Castro, L. Filipe C., Bourguet, William, Schubert, Michael, Laudet, Vincent
Format: Artigo
Language:Inglês
Published: Endocrine Society 2014
Subjects:
General Endocrinology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4197984/
https://ncbi.nlm.nih.gov/pubmed/25116705
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2014-1181
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