A Mollusk Retinoic Acid Receptor (RAR) Ortholog Sheds Light on the Evolution of Ligand Binding

Nuclear receptors are transcription factors that regulate networks of target genes in response to small molecules. There is a strong bias in our knowledge of these receptors because they were mainly characterized in classical model organisms, mostly vertebrates. Therefore, the evolutionary origins o...

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Detalhes bibliográficos
Main Authors: Gutierrez-Mazariegos, Juliana, Nadendla, Eswar Kumar, Lima, Daniela, Pierzchalski, Keely, Jones, Jace W., Kane, Maureen, Nishikawa, Jun-Ichi, Hiromori, Youhei, Nakanishi, Tsuyoshi, Santos, Miguel M., Castro, L. Filipe C., Bourguet, William, Schubert, Michael, Laudet, Vincent
Formato: Artigo
Idioma:Inglês
Publicado em: Endocrine Society 2014
Assuntos:
General Endocrinology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4197984/
https://ncbi.nlm.nih.gov/pubmed/25116705
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2014-1181
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