A Mollusk Retinoic Acid Receptor (RAR) Ortholog Sheds Light on the Evolution of Ligand Binding

Nuclear receptors are transcription factors that regulate networks of target genes in response to small molecules. There is a strong bias in our knowledge of these receptors because they were mainly characterized in classical model organisms, mostly vertebrates. Therefore, the evolutionary origins o...

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Bibliographische Detailangaben
Hauptverfasser: Gutierrez-Mazariegos, Juliana, Nadendla, Eswar Kumar, Lima, Daniela, Pierzchalski, Keely, Jones, Jace W., Kane, Maureen, Nishikawa, Jun-Ichi, Hiromori, Youhei, Nakanishi, Tsuyoshi, Santos, Miguel M., Castro, L. Filipe C., Bourguet, William, Schubert, Michael, Laudet, Vincent
Format: Artigo
Sprache:Inglês
Veröffentlicht: Endocrine Society 2014
Schlagworte:
General Endocrinology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4197984/
https://ncbi.nlm.nih.gov/pubmed/25116705
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2014-1181
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