CDK9-mediated transcription elongation is required for MYC addiction in hepatocellular carcinoma

One-year survival rates for newly diagnosed hepatocellular carcinoma (HCC) are <50%, and unresectable HCC carries a dismal prognosis owing to its aggressiveness and the undruggable nature of its main genetic drivers. By screening a custom library of shRNAs directed toward known drug targets in a...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Principais autores: Huang, Chun-Hao, Lujambio, Amaia, Zuber, Johannes, Tschaharganeh, Darjus F., Doran, Michael G., Evans, Michael J., Kitzing, Thomas, Zhu, Nan, de Stanchina, Elisa, Sawyers, Charles L., Armstrong, Scott A., Lewis, Jason S., Sherr, Charles J., Lowe, Scott W.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2014
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4197965/
https://ncbi.nlm.nih.gov/pubmed/25128497
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.244368.114
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registros relacionados