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How substrate specificity is imposed on a histone demethylase—lessons from KDM2A

Histone lysine methylation and demethylation regulate histone methylation dynamics, which impacts chromatin structure and function. To read and erase the methylated histone residues, lysine demethylases must specifically recognize the histone sequences and methylated sites and discriminate the degre...

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Hlavní autoři: Tsai, Chi-Lin, Shi, Yang, Tainer, John A.
Médium: Artigo
Jazyk:Inglês
Vydáno: Cold Spring Harbor Laboratory Press 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4197959/
https://ncbi.nlm.nih.gov/pubmed/25128493
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.249755.114
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