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A novel import route for an N-anchor mitochondrial outer membrane protein aided by the TIM23 complex

The membrane topology of Om45 in the yeast mitochondrial outer membrane (OM) is under debate. Here, we confirm that Om45 is anchored to the OM from the intermembrane space (IMS) by its N-terminal hydrophobic segment. We show that import of Om45 requires the presequence receptors, Tom20 and Tom22, an...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Song, Jiyao, Tamura, Yasushi, Yoshihisa, Tohru, Endo, Toshiya
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: BlackWell Publishing Ltd 2014
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4197877/
https://ncbi.nlm.nih.gov/pubmed/24781694
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/embr.201338142
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