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Intramolecular Disulfide Bond of Tim22 Protein Maintains Integrity of the TIM22 Complex in the Mitochondrial Inner Membrane

Mitochondrial proteins require protein machineries called translocators in the outer and inner membranes for import into and sorting to their destination submitochondrial compartments. Among them, the TIM22 complex mediates insertion of polytopic membrane proteins into the inner membrane, and Tim22...

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Autores principales: Okamoto, Hiroaki, Miyagawa, Akiko, Shiota, Takuya, Tamura, Yasushi, Endo, Toshiya
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2014
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3931045/
https://ncbi.nlm.nih.gov/pubmed/24385427
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.543264
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