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A novel import route for an N-anchor mitochondrial outer membrane protein aided by the TIM23 complex
The membrane topology of Om45 in the yeast mitochondrial outer membrane (OM) is under debate. Here, we confirm that Om45 is anchored to the OM from the intermembrane space (IMS) by its N-terminal hydrophobic segment. We show that import of Om45 requires the presequence receptors, Tom20 and Tom22, an...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BlackWell Publishing Ltd
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4197877/ https://ncbi.nlm.nih.gov/pubmed/24781694 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/embr.201338142 |
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