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A novel import route for an N-anchor mitochondrial outer membrane protein aided by the TIM23 complex

The membrane topology of Om45 in the yeast mitochondrial outer membrane (OM) is under debate. Here, we confirm that Om45 is anchored to the OM from the intermembrane space (IMS) by its N-terminal hydrophobic segment. We show that import of Om45 requires the presequence receptors, Tom20 and Tom22, an...

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Bibliografische gegevens
Hoofdauteurs: Song, Jiyao, Tamura, Yasushi, Yoshihisa, Tohru, Endo, Toshiya
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: BlackWell Publishing Ltd 2014
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4197877/
https://ncbi.nlm.nih.gov/pubmed/24781694
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/embr.201338142
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