Intravenous AAV9 efficiently transduces myenteric neurons in neonate and juvenile mice

Gene therapies for neurological diseases with autonomic or gastrointestinal involvement may require global gene expression. Gastrointestinal complications are often associated with Parkinson's disease and autism. Lewy bodies, a pathological hallmark of Parkinson's brains, are routinely ide...

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Autors principals: Gombash, Sara E., Cowley, Christopher J., Fitzgerald, Julie A., Hall, Jodie C. E., Mueller, Christian, Christofi, Fedias L., Foust, Kevin D.
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2014
Matèries:
Neuroscience
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4197761/
https://ncbi.nlm.nih.gov/pubmed/25360081
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnmol.2014.00081
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