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Dephosphorylation and inactivation of NPR2 guanylyl cyclase in granulosa cells contributes to the LH-induced decrease in cGMP that causes resumption of meiosis in rat oocytes

In mammals, the meiotic cell cycle of oocytes starts during embryogenesis and then pauses. Much later, in preparation for fertilization, oocytes within preovulatory follicles resume meiosis in response to luteinizing hormone (LH). Before LH stimulation, the arrest is maintained by diffusion of cycli...

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Библиографические подробности
Главные авторы: Egbert, Jeremy R., Shuhaibar, Leia C., Edmund, Aaron B., Van Helden, Dusty A., Robinson, Jerid W., Uliasz, Tracy F., Baena, Valentina, Geerts, Andreas, Wunder, Frank, Potter, Lincoln R., Jaffe, Laurinda A.
Формат: Artigo
Язык:Inglês
Опубликовано: The Company of Biologists 2014
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4197715/
https://ncbi.nlm.nih.gov/pubmed/25183874
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.112219
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