Luteinizing Hormone Reduces the Activity of the NPR2 Guanylyl Cyclase in Mouse Ovarian Follicles, Contributing to the Cyclic GMP Decrease that Promotes Resumption of Meiosis in Oocytes

In preovulatory ovarian follicles of mice, meiotic prophase arrest in the oocyte is maintained by cyclic GMP from the surrounding granulosa cells that diffuses into the oocyte through gap junctions. The cGMP is synthesized in the granulosa cells by the transmembrane guanylyl cyclase natriuretic pept...

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Détails bibliographiques
Auteurs principaux: Robinson, Jerid W., Zhang, Meijia, Shuhaibar, Leia C., Norris, Rachael P., Geerts, Andreas, Wunder, Frank, Eppig, John J., Potter, Lincoln R., Jaffe, Laurinda A.
Format: Artigo
Langue:Inglês
Publié: 2012
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3358460/
https://ncbi.nlm.nih.gov/pubmed/22546688
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2012.04.019
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