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Activation of the Lck tyrosine protein kinase by hydrogen peroxide requires the phosphorylation of Tyr-394.

Exposure of cells to H2O2 mimics many of the effects of treatment of cells with extracellular ligands. Among these is the stimulation of tyrosine phosphorylation. In this study, we show that exposure of cells to H2O2 increases the catalytic activity of the lymphocyte-specific tyrosine protein kinase...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Principais autores: Hardwick, J S, Sefton, B M
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1995
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC41977/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7538674/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.92.10.4527
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