Single-cell analyses of regulatory network perturbations using enhancer-targeting TALEs suggest novel roles for PU.1 during haematopoietic specification

Transcription factors (TFs) act within wider regulatory networks to control cell identity and fate. Numerous TFs, including Scl (Tal1) and PU.1 (Spi1), are known regulators of developmental and adult haematopoiesis, but how they act within wider TF networks is still poorly understood. Transcription...

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Detaylı Bibliyografya
Asıl Yazarlar: Wilkinson, Adam C., Kawata, Viviane K. S., Schütte, Judith, Gao, Xuefei, Antoniou, Stella, Baumann, Claudia, Woodhouse, Steven, Hannah, Rebecca, Tanaka, Yosuke, Swiers, Gemma, Moignard, Victoria, Fisher, Jasmin, Hidetoshi, Shimauchi, Tijssen, Marloes R., de Bruijn, Marella F. T. R., Liu, Pentao, Göttgens, Berthold
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: The Company of Biologists 2014
Konular:
Techniques and Resources
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4197694/
https://ncbi.nlm.nih.gov/pubmed/25252941
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.115709
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