Single-cell analyses of regulatory network perturbations using enhancer-targeting TALEs suggest novel roles for PU.1 during haematopoietic specification

Transcription factors (TFs) act within wider regulatory networks to control cell identity and fate. Numerous TFs, including Scl (Tal1) and PU.1 (Spi1), are known regulators of developmental and adult haematopoiesis, but how they act within wider TF networks is still poorly understood. Transcription...

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Main Authors: Wilkinson, Adam C., Kawata, Viviane K. S., Schütte, Judith, Gao, Xuefei, Antoniou, Stella, Baumann, Claudia, Woodhouse, Steven, Hannah, Rebecca, Tanaka, Yosuke, Swiers, Gemma, Moignard, Victoria, Fisher, Jasmin, Hidetoshi, Shimauchi, Tijssen, Marloes R., de Bruijn, Marella F. T. R., Liu, Pentao, Göttgens, Berthold
Formato: Artigo
Idioma:Inglês
Publicado em: The Company of Biologists 2014
Assuntos:
Techniques and Resources
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4197694/
https://ncbi.nlm.nih.gov/pubmed/25252941
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.115709
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