Deletion of Rbpj from postnatal endothelium leads to abnormal arteriovenous shunting in mice

Arteriovenous malformations (AVMs) are tortuous vessels characterized by arteriovenous (AV) shunts, which displace capillaries and shunt blood directly from artery to vein. Notch signaling regulates embryonic AV specification by promoting arterial, as opposed to venous, endothelial cell (EC) fate. T...

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Autors principals: Nielsen, Corinne M., Cuervo, Henar, Ding, Vivianne W., Kong, Yupeng, Huang, Eric J., Wang, Rong A.
Format: Artigo
Idioma:Inglês
Publicat: The Company of Biologists 2014
Matèries:
Research Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4197591/
https://ncbi.nlm.nih.gov/pubmed/25209249
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.108951
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