FSP-1 Impairs the Function of Endothelium Leading to Failure of Arteriovenous Grafts in Diabetic Mice

To understand how endothelial cell (EC) dysfunction contributes to the failure of arteriovenous graft (AVG), we investigated the role of fibroblast-specific protein 1 (FSP-1) in cultured ECs and a mouse AVG model. In vitro, we uncovered a new FSP-1-dependent pathway that activates rho-associated, co...

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Bibliografiske detaljer
Udgivet i:Endocrinology
Main Authors: Luo, Jinlong, Liang, Ming, Mitch, William E., Danesh, Farhad R., Yu, Michael, Cheng, Jizhong
Format: Artigo
Sprog:Inglês
Udgivet: Endocrine Society 2015
Fag:
Original Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4430603/
https://ncbi.nlm.nih.gov/pubmed/25774552
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2014-1841
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