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Deletion of Rbpj from postnatal endothelium leads to abnormal arteriovenous shunting in mice
Arteriovenous malformations (AVMs) are tortuous vessels characterized by arteriovenous (AV) shunts, which displace capillaries and shunt blood directly from artery to vein. Notch signaling regulates embryonic AV specification by promoting arterial, as opposed to venous, endothelial cell (EC) fate. T...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Company of Biologists
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4197591/ https://ncbi.nlm.nih.gov/pubmed/25209249 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.108951 |
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