Phosphoinositide 3-kinase p85beta regulates invadopodium formation

The acquisition of invasiveness is characteristic of tumor progression. Numerous genetic changes are associated with metastasis, but the mechanism by which a cell becomes invasive remains unclear. Expression of p85β, a regulatory subunit of phosphoinositide-3-kinase, markedly increases in advanced c...

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Bibliographische Detailangaben
Hauptverfasser: Cariaga-Martínez, Ariel E., Cortés, Isabel, García, Esther, Pérez-García, Vicente, Pajares, María J., Idoate, Miguel A., Redondo-Muñóz, Javier, Antón, Inés M., Carrera, Ana C.
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Company of Biologists 2014
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4197441/
https://ncbi.nlm.nih.gov/pubmed/25217619
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/bio.20148185
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