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Serine integrase chimeras with activity in E. coli and HeLa cells

In recent years, application of serine integrases for genomic engineering has increased in popularity. The factor-independence and unidirectionality of these large serine recombinases makes them well suited for reactions such as site-directed vector integration and cassette exchange in a wide variet...

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Autors principals: Farruggio, Alfonso P., Calos, Michele P.
Format: Artigo
Idioma:Inglês
Publicat: The Company of Biologists 2014
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4197438/
https://ncbi.nlm.nih.gov/pubmed/25217617
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/bio.20148748
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