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Top-Down and Bottom-Up Identification of Proteins by Liquid Extraction Surface Analysis Mass Spectrometry of Healthy and Diseased Human Liver Tissue

Liquid extraction surface analysis mass spectrometry (LESA MS) has the potential to become a useful tool in the spatially-resolved profiling of proteins in substrates. Here, the approach has been applied to the analysis of thin tissue sections from human liver. The aim was to determine whether LESA...

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Detalles Bibliográficos
Main Authors: Sarsby, Joscelyn, Martin, Nicholas J., Lalor, Patricia F., Bunch, Josephine, Cooper, Helen J.
Formato: Artigo
Idioma:Inglês
Publicado: Springer US 2014
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4197381/
https://ncbi.nlm.nih.gov/pubmed/25183224
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13361-014-0967-z
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