Clinical features of De Novo acute myeloid leukemia with concurrent DNMT3A, FLT3 and NPM1 mutations

BACKGROUND: De novo acute myeloid leukemia (AML) with concurrent DNMT3A, FLT3 and NPM1 mutations (AML(DNMT3A/FLT3/NPM1)) has been suggested to represent a unique AML subset on the basis of integrative genomic analysis, but the clinical features of such patients have not been characterized systematic...

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Autores principales: Loghavi, Sanam, Zuo, Zhuang, Ravandi, Farhad, Kantarjian, Hagop M, Bueso-Ramos, Carlos, Zhang, Liping, Singh, Rajesh R, Patel, Keyur P, Medeiros, L Jeffrey, Stingo, Francesco, Routbort, Mark, Cortes, Jorge, Luthra, Rajyalakshmi, Khoury, Joseph D
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2014
Materias:
Research
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4197326/
https://ncbi.nlm.nih.gov/pubmed/25281355
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13045-014-0074-4
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