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Inactivation of Bcl-2 by phosphorylation.

The antiapoptosis potential of Bcl-2 protein is well established, but the mechanism of Bcl-2 action is still poorly understood. Using the phosphatase inhibitor okadaic acid or the chemotherapeutic drug taxol, we found that Bcl-2 was phosphorylated in lymphoid cells. Phospho amino acid analysis revea...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Principais autores: Haldar, S, Jena, N, Croce, C M
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1995
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC41973/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7753834/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.92.10.4507
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