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Catechins induced acute promyelocytic leukemia cell apoptosis and triggered PML-RARα oncoprotein degradation

BACKGROUND: It has recently been reported that the extracts of green tea polyphenol have cancer preventive effects. In this study, we investigated the effect of the natural composition from green tea leaves Catechins on acute promyelocytic leukemia (APL). METHODS: In vitro, APL cell lines NB4, retin...

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Bibliographic Details
Main Authors: Zhang, Li, Chen, Qiu-Sheng, Xu, Peng-Peng, Qian, Ying, Wang, Ai-Hua, Xiao, Dan, Zhao, Yan, Sheng, Yan, Wen, Xiang-Qin, Zhao, Wei-Li
Format: Artigo
Language:Inglês
Published: BioMed Central 2014
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4197244/
https://ncbi.nlm.nih.gov/pubmed/25270015
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13045-014-0075-3
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