Nf2/merlin regulates hematopoietic stem cell behavior by altering microenvironmental architecture

Stem cell population size is highly regulated across species and tissue types and alterations are associated with premature tissue failure or cancer. We assessed whether the tumor suppressor and mediator of cell contact inhibition Nf2/merlin plays a role in governing the hematopoietic stem cell pool...

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Main Authors: Larsson, Jonas, Ohishi, Masanobu, Garrison, Brian, Aspling, Marie, Janzen, Viktor, Adams, Gregor B, Curto, Marcello, McClatchey, Andrea I, Schipani, Ernestina, Scadden, David T
Format: Artigo
Sprog:Inglês
Udgivet: 2008
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4197168/
https://ncbi.nlm.nih.gov/pubmed/18682243
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stem.2008.06.005
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