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Nf2/Merlin controls progenitor homeostasis and tumorigenesis in the liver

The molecular signals that control the maintenance and activation of liver stem/progenitor cells are poorly understood, and the role of liver progenitor cells in hepatic tumorigenesis is unclear. We report here that liver-specific deletion of the neurofibromatosis type 2 (Nf2) tumor suppressor gene...

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Autors principals: Benhamouche, Samira, Curto, Marcello, Saotome, Ichiko, Gladden, Andrew B., Liu, Ching-Hui, Giovannini, Marco, McClatchey, Andrea I.
Format: Artigo
Idioma:Inglês
Publicat: Cold Spring Harbor Laboratory Press 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2922501/
https://ncbi.nlm.nih.gov/pubmed/20675406
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1938710
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