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Localization to the Cortical Cytoskeleton Is Necessary for Nf2/Merlin-Dependent Epidermal Growth Factor Receptor Silencing

Merlin, the product of the NF2 tumor suppressor gene, is closely related to the ERM (ezrin, radixin, moesin) proteins, which provide anchorage between membrane proteins and the underlying cortical cytoskeleton; all four proteins are members of the band 4.1 superfamily. Despite their similarity, the...

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Autors principals: Cole, Banumathi K., Curto, Marcello, Chan, Annie W., McClatchey, Andrea I.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology (ASM) 2008
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2258752/
https://ncbi.nlm.nih.gov/pubmed/18086884
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01139-07
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