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Localization to the Cortical Cytoskeleton Is Necessary for Nf2/Merlin-Dependent Epidermal Growth Factor Receptor Silencing

Merlin, the product of the NF2 tumor suppressor gene, is closely related to the ERM (ezrin, radixin, moesin) proteins, which provide anchorage between membrane proteins and the underlying cortical cytoskeleton; all four proteins are members of the band 4.1 superfamily. Despite their similarity, the...

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Detalles Bibliográficos
Autores principales: Cole, Banumathi K., Curto, Marcello, Chan, Annie W., McClatchey, Andrea I.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology (ASM) 2008
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2258752/
https://ncbi.nlm.nih.gov/pubmed/18086884
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01139-07
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