The Nf2 Tumor Suppressor, Merlin, Regulates Epidermal Development Through the Establishment of a Junctional Polarity Complex

The neurofibromatosis type 2 (NF2) tumor suppressor, Merlin, is a FERM (Four point one, Ezrin, Radixin, Moesin) domain-containing protein whose loss results in defective morphogenesis and tumorigenesis in multiple tissues. Like the closely related ERM proteins (Ezrin, Radixin and Moesin), Merlin may...

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Bibliografiske detaljer
Main Authors: Gladden, Andrew B., Hebert, Alan M., Schneeberger, Eveline E., McClatchey, Andrea I.
Format: Artigo
Sprog:Inglês
Udgivet: 2010
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3033574/
https://ncbi.nlm.nih.gov/pubmed/21074722
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2010.10.008
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