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Integrated Control Of Hepatic Lipogenesis Vs. Glucose Production Requires FoxO Transcription Factors
Insulin integrates hepatic glucose and lipid metabolism, directing nutrients to storage as glycogen and triglyceride. In type 2 diabetes, levels of the former are low and the latter are exaggerated, posing a pathophysiologic and therapeutic conundrum. A branching model of insulin signaling, with Fox...
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Main Authors: | , , , , , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2014
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4197140/ https://ncbi.nlm.nih.gov/pubmed/25307742 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms6190 |
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