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Kinetochores require oligomerization of Dam1 complex to maintain microtubule attachments against tension and promote biorientation
Kinetochores assemble on centromeric DNA and present arrays of proteins that attach directly to the dynamic ends of microtubules. Kinetochore proteins coordinate at the microtubule interface through oligomerization, but how oligomerization contributes to kinetochore function has remained unclear. He...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4197110/ https://ncbi.nlm.nih.gov/pubmed/25236177 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms5951 |
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