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Cdk1 Phosphorylation of the Dam1 Complex Strengthens Kinetochore-Microtubule Attachments

To ensure the faithful inheritance of DNA, a macromolecular protein complex called the kinetochore sustains the connection between chromosomes and force-generating dynamic microtubules during cell division. Defects in this process lead to aneuploidy, a common feature of cancer cells and the cause of...

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Publicat a:Curr Biol
Autors principals: Gutierrez, Abraham, Kim, Jae ook, Umbreit, Neil T., Asbury, Charles L., Davis, Trisha N., Miller, Matthew P., Biggins, Sue
Format: Artigo
Idioma:Inglês
Publicat: The Author(s). Published by Elsevier Inc. 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7497780/
https://ncbi.nlm.nih.gov/pubmed/32946748
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cub.2020.08.054
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