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Structural Characteristic of the Initial Unfolded State on Refolding Determines Catalytic Efficiency of the Folded Protein in Presence of Osmolytes

Osmolytes are low molecular weight organic molecules accumulated by organisms to assist proper protein folding, and to provide protection to the structural integrity of proteins under denaturing stress conditions. It is known that osmolyte-induced protein folding is brought by unfavorable interactio...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Warepam, Marina, Sharma, Gurumayum Suraj, Dar, Tanveer Ali, Khan, Md. Khurshid Alam, Singh, Laishram Rajendrakumar
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Public Library of Science 2014
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4196897/
https://ncbi.nlm.nih.gov/pubmed/25313668
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0109408
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