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Existence of Molten Globule State in Homocysteine-Induced Protein Covalent Modifications

Homocysteine thiolactone is a toxic metabolite produced from homocysteine by amino-acyl t-RNA synthetase in error editing reaction. The basic cause of toxicity of homocysteine thiolactone is believed to be due to the adduct formation with lysine residues (known as protein N-homocysteinylation) leadi...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Kumar, Tarun, Sharma, Gurumayum Suraj, Singh, Laishram Rajendrakumar
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4236184/
https://ncbi.nlm.nih.gov/pubmed/25405350
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0113566
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