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Existence of Molten Globule State in Homocysteine-Induced Protein Covalent Modifications
Homocysteine thiolactone is a toxic metabolite produced from homocysteine by amino-acyl t-RNA synthetase in error editing reaction. The basic cause of toxicity of homocysteine thiolactone is believed to be due to the adduct formation with lysine residues (known as protein N-homocysteinylation) leadi...
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| Udgivet i: | PLoS One |
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| Main Authors: | , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Public Library of Science
2014
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4236184/ https://ncbi.nlm.nih.gov/pubmed/25405350 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0113566 |
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