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Failure of cell cleavage induces senescence in tetraploid primary cells
Tetraploidy can arise from various mitotic or cleavage defects in mammalian cells, and inheritance of multiple centrosomes induces aneuploidy when tetraploid cells continue to cycle. Arrest of the tetraploid cell cycle is therefore potentially a critical cellular control. We report here that primary...
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| Main Authors: | , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
The American Society for Cell Biology
2014
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4196863/ https://ncbi.nlm.nih.gov/pubmed/25143403 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E14-03-0844 |
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