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Glioblastoma motility occurs in the absence of actin polymer

In fibroblasts and keratocytes, motility is actin dependent, while microtubules play a secondary role, providing directional guidance. We demonstrate here that the motility of glioblastoma cells is exceptional, in that it occurs in cells depleted of assembled actin. Cells display persistent motility...

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Autori principali: Panopoulos, Andreas, Howell, Michael, Fotedar, Rati, Margolis, Robert L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: The American Society for Cell Biology 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3128524/
https://ncbi.nlm.nih.gov/pubmed/21551075
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E10-10-0849
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