Cardiac interstitial tetraploid cells can escape replicative senescence in rodents but not large mammals

Cardiomyocyte ploidy has been described but remains obscure in cardiac interstitial cells. Ploidy of c-kit+ cardiac interstitial cells was assessed using confocal, karyotypic, and flow cytometric technique. Notable differences were found between rodent (rat, mouse) c-kit+ cardiac interstitial cells...

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Detalhes bibliográficos
Publicado no:Commun Biol
Main Authors: Broughton, Kathleen M., Khieu, Tiffany, Nguyen, Nicky, Rosa, Michael, Mohsin, Sadia, Quijada, Pearl, Wang, Bingyan J., Echeagaray, Oscar H., Kubli, Dieter A., Kim, Taeyong, Firouzi, Fareheh, Monsanto, Megan M., Gude, Natalie A., Adamson, Robert M., Dembitsky, Walter P., Davis, Michael E., Sussman, Mark A.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6565746/
https://ncbi.nlm.nih.gov/pubmed/31231694
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s42003-019-0453-z
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