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Two Structural Motifs within Canonical EF-Hand Calcium-Binding Domains Identify Five Different Classes of Calcium Buffers and Sensors

Proteins with EF-hand calcium-binding motifs are essential for many cellular processes, but are also associated with cancer, autism, cardiac arrhythmias, and Alzheimer's, skeletal muscle and neuronal diseases. Functionally, all EF-hand proteins are divided into two groups: (1) calcium sensors,...

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Detalhes bibliográficos
Main Authors: Denessiouk, Konstantin, Permyakov, Sergei, Denesyuk, Alexander, Permyakov, Eugene, Johnson, Mark S.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4196763/
https://ncbi.nlm.nih.gov/pubmed/25313560
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0109287
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