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Constitutive association of the proapoptotic protein Bim with Bcl-2-related proteins on mitochondria in T cells
Apoptosis in activated T cells in vivo requires the proapoptotic Bcl-2 family member Bim. We show here that, despite its ability to bind LC8, a component of the microtubule dynein motor complex, most of the Bim in both healthy and apoptotic T cells is associated with mitochondria, not microtubules....
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| Main Authors: | , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2004
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC419666/ https://ncbi.nlm.nih.gov/pubmed/15136728 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0402293101 |
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