Functional interactions of RNA-capping enzyme with factors that positively and negatively regulate promoter escape by RNA polymerase II

Capping of the 5′ ends of nascent RNA polymerase II transcripts is the first pre-mRNA processing event in all eukaryotic cells. Capping enzyme (CE) is recruited to transcription complexes soon after initiation by the phosphorylation of Ser-5 of the carboxyl-terminal domain of the largest subunit of...

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Udgivet i:Proc Natl Acad Sci U S A
Main Authors: Mandal, Subhrangsu S., Chu, Chun, Wada, Tadashi, Handa, Hiroshi, Shatkin, Aaron J., Reinberg, Danny
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2004
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC419647/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15136722/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.0401493101
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