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Inducing and modulating anisotropic DNA bends by pseudocomplementary peptide nucleic acids

DNA bending is significant for various DNA functions in the cell. Here, we demonstrate that pseudocomplementary peptide nucleic acids (pcPNAs) represent a class of versatile, sequence-specific DNA-bending agents. The occurrence of anisotropic DNA bends induced by pcPNAs is shown by gel electrophoret...

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Main Authors: Kuhn, Heiko, Cherny, Dmitry I., Demidov, Vadim V., Frank-Kamenetskii, Maxim D.
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 2004
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC419643/
https://ncbi.nlm.nih.gov/pubmed/15136738
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0308756101
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