Balanced-PCR amplification allows unbiased identification of genomic copy changes in minute cell and tissue samples

Analysis of genomic DNA derived from cells and fresh or fixed tissues often requires whole genome amplification prior to microarray screening. Technical hurdles to this process are the introduction of amplification bias and/or the inhibitory effects of formalin fixation on DNA amplification. Here we...

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Detalhes bibliográficos
Main Authors: Wang, Gang, Brennan, Cameron, Rook, Martha, Wolfe, Jia Liu, Leo, Christopher, Chin, Lynda, Pan, Hongjie, Liu, Wei-Hua, Price, Brendan, Makrigiorgos, G. Mike
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2004
Assuntos:
NAR Methods Online
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC419625/
https://ncbi.nlm.nih.gov/pubmed/15155823
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gnh070
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