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Balanced-PCR amplification allows unbiased identification of genomic copy changes in minute cell and tissue samples
Analysis of genomic DNA derived from cells and fresh or fixed tissues often requires whole genome amplification prior to microarray screening. Technical hurdles to this process are the introduction of amplification bias and/or the inhibitory effects of formalin fixation on DNA amplification. Here we...
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| Autori principali: | , , , , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Oxford University Press
2004
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC419625/ https://ncbi.nlm.nih.gov/pubmed/15155823 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gnh070 |
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