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Balanced-PCR amplification allows unbiased identification of genomic copy changes in minute cell and tissue samples

Analysis of genomic DNA derived from cells and fresh or fixed tissues often requires whole genome amplification prior to microarray screening. Technical hurdles to this process are the introduction of amplification bias and/or the inhibitory effects of formalin fixation on DNA amplification. Here we...

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Udgivet i:Nucleic Acids Res
Principais autores: Wang, Gang, Brennan, Cameron, Rook, Martha, Wolfe, Jia Liu, Leo, Christopher, Chin, Lynda, Pan, Hongjie, Liu, Wei-Hua, Price, Brendan, Makrigiorgos, G. Mike
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2004
Fag:
NAR Methods Online
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC419625/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15155823/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/gnh070
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