Balanced-PCR amplification allows unbiased identification of genomic copy changes in minute cell and tissue samples

Analysis of genomic DNA derived from cells and fresh or fixed tissues often requires whole genome amplification prior to microarray screening. Technical hurdles to this process are the introduction of amplification bias and/or the inhibitory effects of formalin fixation on DNA amplification. Here we...

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Bibliografiska uppgifter
Huvudupphovsmän: Wang, Gang, Brennan, Cameron, Rook, Martha, Wolfe, Jia Liu, Leo, Christopher, Chin, Lynda, Pan, Hongjie, Liu, Wei-Hua, Price, Brendan, Makrigiorgos, G. Mike
Materialtyp: Artigo
Språk:Inglês
Publicerad: Oxford University Press 2004
Ämnen:
NAR Methods Online
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC419625/
https://ncbi.nlm.nih.gov/pubmed/15155823
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gnh070
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