Deletion of Ptprd and Cdkn2a cooperate to accelerate tumorigenesis

PTPRD encodes the protein tyrosine phosphatase receptor type D and is frequently inactivated across many human cancers. Despite its frequent inactivation, it is unknown whether loss of PTPRD promotes tumorigenesis in vivo. PTPRD is located on chromosome 9p, as is CDKN2A, and the two loci are frequen...

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Hlavní autoři: Ortiz, Berenice, White, Julie R., Wu, Wei H., Chan, Timothy A.
Médium: Artigo
Jazyk:Inglês
Vydáno: Impact Journals LLC 2014
Témata:
Research Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4196177/
https://ncbi.nlm.nih.gov/pubmed/25138050
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