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SAG/RBX2 is a novel substrate of NEDD4-1 E3 ubiquitin ligase and mediates NEDD4-1 induced chemosensitization

Sensitive to apoptosis gene (SAG), also known as RBX2, ROC2, or RNF7, is a RING component of SCF E3 ubiquitin ligases, which regulates cellular functions through ubiquitylation and degradation of many protein substrates. Although our previous studies showed that SAG is transcriptionally induced by r...

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Bibliografske podrobnosti
Main Authors: Zhou, Weihua, Xu, Jie, Zhao, Yongchao, Sun, Yi
Format: Artigo
Jezik:Inglês
Izdano: Impact Journals LLC 2014
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4196160/
https://ncbi.nlm.nih.gov/pubmed/25216516
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