Role of Bcl-xL/Beclin-1 in synergistic apoptotic effects of secretory TRAIL-armed adenovirus in combination with mitomycin C and hyperthermia on colon cancer cells

In this study, we attempted to develop a multimodality approach using chemotherapeutic agent mitomycin C, biologic agent tumor necrosis factor-related apoptosis-inducing ligand (TRAIL/Apo-2L), and mild hyperthermia to treat colon cancer. For this study, human colon cancer LS174T, LS180, HCT116 and C...

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Detalles Bibliográficos
Main Authors: Kim, Seog-Young, Lee, Dae-Hee, Song, Xinxin, Bartlett, David L., Kwon, Yong Tae, Lee, Yong J.
Formato: Artigo
Idioma:Inglês
Publicado: Springer US 2014
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Original Paper
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4196052/
https://ncbi.nlm.nih.gov/pubmed/25156145
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10495-014-1028-6
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