High-throughput multiplex HLA genotyping by next-generation sequencing using multi-locus individual tagging

BACKGROUND: Unambiguous human leukocyte antigen (HLA) typing is important in transplant matching and disease association studies. High-resolution HLA typing that is not restricted to the peptide-binding region can decrease HLA allele ambiguities. Cost and technology constraints have hampered high-th...

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Detalhes bibliográficos
Main Authors: Ehrenberg, Philip K, Geretz, Aviva, Baldwin, Karen M, Apps, Richard, Polonis, Victoria R, Robb, Merlin L, Kim, Jerome H, Michael, Nelson L, Thomas, Rasmi
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
Assuntos:
Methodology Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4196003/
https://ncbi.nlm.nih.gov/pubmed/25283548
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-15-864
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