Characterization of Dystrophin Deficient Rats: A New Model for Duchenne Muscular Dystrophy

A few animal models of Duchenne muscular dystrophy (DMD) are available, large ones such as pigs or dogs being expensive and difficult to handle. Mdx (X-linked muscular dystrophy) mice only partially mimic the human disease, with limited chronic muscular lesions and muscle weakness. Their small size...

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Autori principali: Larcher, Thibaut, Lafoux, Aude, Tesson, Laurent, Remy, Séverine, Thepenier, Virginie, François, Virginie, Le Guiner, Caroline, Goubin, Helicia, Dutilleul, Maéva, Guigand, Lydie, Toumaniantz, Gilles, De Cian, Anne, Boix, Charlotte, Renaud, Jean-Baptiste, Cherel, Yan, Giovannangeli, Carine, Concordet, Jean-Paul, Anegon, Ignacio, Huchet, Corinne
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2014
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4195719/
https://ncbi.nlm.nih.gov/pubmed/25310701
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0110371
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