Confirmation of Childhood Acute Lymphoblastic Leukemia Variants, ARID5B and IKZF1, and Interaction with Parental Environmental Exposures

Genome wide association studies (GWAS) have established association of ARID5B and IKZF1 variants with childhood acute lymphoblastic leukemia (ALL). Epidemiological studies suggest that environmental factors alone appear to make a relatively minor contribution to disease risk. The polygenic nature of...

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Bibliografiska uppgifter
Huvudupphovsmän: Evans, Tiffany-Jane, Milne, Elizabeth, Anderson, Denise, de Klerk, Nicholas H., Jamieson, Sarra E., Talseth-Palmer, Bente A., Bowden, Nikola A., Holliday, Elizabeth G., Rudant, Jérémie, Orsi, Laurent, Richardson, Ebony, Lavis, Laura, Catchpoole, Daniel, Attia, John R., Armstrong, Bruce K., Clavel, Jacqueline, Scott, Rodney J.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Public Library of Science 2014
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4195717/
https://ncbi.nlm.nih.gov/pubmed/25310577
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0110255
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