Lentiviral Delivery of PPARγ shRNA Alters the Balance of Osteogenesis and Adipogenesis, Improving Bone Microarchitecture

Introduction: Skeletal aging is associated not only with alterations in osteoblast (OB) and osteoclast (OC) number and activity within the basic metabolic unit, but also with increased marrow adiposity. Peroxisome proliferator-activated receptor gamma (PPARγ) is commonly considered the master transc...

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Detalhes bibliográficos
Main Authors: James, Aaron W., Shen, Jia, Khadarian, Kevork, Pang, Shen, Chung, Greg, Goyal, Raghav, Asatrian, Greg, Velasco, Omar, Kim, Jung, Zhang, Xinli, Ting, Kang, Soo, Chia
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc. 2014
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Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4195482/
https://ncbi.nlm.nih.gov/pubmed/24785569
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/ten.tea.2013.0736
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