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Φ-Value analysis and the nature of protein-folding transition states

Φ values are used to map structures of protein-folding transition states from changes in free energies of denaturation (ΔΔG(D-N)) and activation on mutation. A recent reappraisal proposed that Φ values for ΔΔG(D-N) < 1.7 kcal/mol are artifactual. On discarding such derived Φ values from published...

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Detaylı Bibliyografya
Asıl Yazarlar: Fersht, Alan R., Sato, Satoshi
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: National Academy of Sciences 2004
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC419542/
https://ncbi.nlm.nih.gov/pubmed/15150406
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0402684101
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