Mapping quantitative traits with random and with ascertained sibships
Use of a robust score statistic based on a variance components model to map quantitative trait loci in randomly sampled pedigrees is reviewed. Sibships ascertained through a single proband are discussed. Under a standard assumption of multivariate normality, two suggested methods of ascertainment co...
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| Publicat a: | Proc Natl Acad Sci U S A |
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| Autors principals: | , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
National Academy of Sciences
2004
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC419519/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15084737/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.0401713101 |
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